About Xiaowen Liu
Dr. Liu’s research is focused on human nutritional and metabolic dysfunction in the critically ill patients. After completing 6 years of the Interdepartmental Graduate Program in Nutritional Sciences and statistics in university of Wisconsin- Madison, and 3.5 years of postdoctoral training in endocrinology at Beth Israel Deaconess Medical Center, Harvard Medical School, Dr. Liu has developed an area of expertise in basic science research, biostatistics and data analysis which is critical for success in translational research. After completion of my post-doctoral training, I became the Lab Director at the Center for Resuscitation Science in BIDMC, which is a multi-disciplinary group of investigators focused on translational research with an emphasis on metabolic and mitochondrial dysfunction in the critically ill. As laboratory director I am providing an excellent bridge between clinical investigation and basic science. My research on immunocapture and microplate-based activity and quantity measurement of pyruvate dehydrogenase in human peripheral blood mononuclear cells set is a novel, easy and less invasive way to further understand the role of PDH, a key enzyme linking the glycolysis metabolic pathway to the citric acid cycle and releasing energy via NADH, in human disease. My current work is focused on evaluating mitochondrial and metabolic dysfunction across a range of critical illness and the response to potential metabolic resuscitators both in the lab and clinical setting.