Pancreatitis Research
The Center of Resuscitation Science has recently formed a unique clinical research collaboration with the Pancreas Center at BIDMC. The Pancreas Center is an internationally renowned program that provides expertise in diagnosing and managing exocrine pancreatic diseases under the leadership of Dr. Steven Freedman and Dr. Sunil Sheth. By working closely with the Intensive Care Unit and other patient care units at BIDMC to offer the highest level of care for patients with pancreatitis.
As part of our commitment to providing excellent patient care and high-class research, we have collaborated with them to bring opportunities for patients to participate in ongoing clinical research projects to improve outcomes in patients with acute pancreatitis through our CRISP (Corticosteroids to Reduce Inflammation in Severe Pancreatitis) study lead by Dr. Michael W. Donnino. We are happy to accept referrals.
If you have a referral for the Pancreas Center, please call 617-667-5576. For more information regarding ongoing clinical trials, please click here or contact us at CRSRAteam@bidmc.harvard.edu.
MEET THE LEADERSHIP TEAM
ABOUT CRISP
Co-investigators:
- Michael Donnino
- Steve Freedman
- Kate Berg
- Michael Cocchi
- Anne Grossestruer
- Lakshman Balaji
- Xiaowen Liu
- Noa Berlin
- Jacob Vine
- Ankit Chhoda
Study Staff
- Franklin Li
- Shivani Mehta
- Jeremy Silverman
- Alan Berkovitz
- Max Meier
Abstract
Pancreatitis is a common and potentially lethal and/or debilitating condition for which existing treatment options have shown limited efficacy. Since inflammation is a key driver of disease progression in pancreatitis, we are conducting a Phase II randomized clinical trial to establish whether a brief course of anti-inflammatory corticosteroids given very early in the acute process will improve key clinical outcomes including illness severity, inflammation, and pancreatic injury, hospital and ICU-free days, and death. We are currently enrolling adult patients with severe acute pancreatitis admitted to BIDMC or to Montifiore Medical Center (New York City). Please click here for more information.
Number of Patients Enrolled:
24