About Maureen Chase
Dr. Maureen Chase began her research career at the Hospital of the University of Pennsylvania with a clinical research fellowship in the risk stratification of Emergency Department patients with chest pain. After joining the faculty at BIDMC, she continued her work in the early identification of patients with critical illnesses while working towards her Master in Public Health degree at the Harvard School of Public Health, publishing her work in the identification of patients with sepsis and bacteremia. She was awarded a Harvard Catalyst Pilot grant for her prospective investigation into patients with dizziness at risk for stroke that involved collaboration between the Emergency Departments at the three Harvard teaching hospitals. Via her MPH training and work within the Center for Resuscitation Science, Dr. Chase’s research focus transitioned toward early interventions for patients with critical illness. In 2013, she was awarded a K23 Mentored Patient-Oriented Research Career Development Award via the NIH/ NIGMS for her project “Statin Therapy in Acute Influenza”. The study is a randomized controlled trial assessing the effect of atorvastatin on the host inflammatory response to influenza with both clinical and laboratory endpoints.
Topics for Talks by Maureen Chase
- Statins in Influenza
- Basics in Clinical Trial Design and Execution
Latest Publications
- Ilg A, Moskowitz A, Konanki V, Patel PV, Chase M, Grossestreuer AV, Donnino MW. Performance of the CURB-65 Score in Predicting Critical Care Interventions in Patients Admitted with Community-Acquired Pneumonia. Ann Emerg Med. 2018 Aug; [Epub ahead of print].
- Chase M, Cocchi MN, Liu X, Andersen LW, Holmberg M, Donnino MW. Coenzyme Q10 in Acute Influenza. Influenza Other Respir Viruses. 2018 Aug: [Epub ahead of print].
- Karlsson CM, Donnino MW, Kirkegaard H, Cocchi MN, Chase M, Andersen LW. Acute Respiratory Compromise in the Emergency Department: A Description and Analysis of 3571 Events from the Get with the Guidelines-Resuscitation Registry. Journal of Emergency Medicine. 2017 Apr; 52(4):393-402.
- Moskowitz A, Omar Y, Chase M, Lockhandwala S, Chase M, Patel PV, Andersen LW, Cocchi MN, Donnino MW. Reasons for Death in Patients with Sepsis and Septic Shock. Journal of Critical Care. 2017 Apr;38:284-288.
- Nadler J, Stankovic N, Uber AJ, Holmberg MJ, Sanchez L, Chase M, Wolfe R, Donnino MW, Cocchi MN. Outcomes in variceal hemorrhage following the use of a balloon tamponade device. Am J Emerg Med. 2017 Oct;35(10):1500-1502.
- Moskowitz A, Andersen LW, Karlsson M, Grossestreuer AV, Chase M, Cocchi MN, Berg K, Donnino MW. Predicting In-Hospital Mortality for Initial Survivors of Acute Respiratory Compromise (ARC) events: Development and Validation of the ARC Score. Resuscitation. 2017 Jun;115:5-10.
- Moskowitz A, Patel PV, Grossestreuer AV, Chase M, Shapiro NI, Berg K, Cocchi MN, Holmberg MJ, Donnino MW; Center for Resuscitation Science. Quick Sequential Organ Failure Assessment and Systemic Inflammatory Response Syndrome Criteria as Predictors of Critical Care Intervention Among Patients With Suspected Infection. Crit Care Med. 2017 Nov;45(11):1813-1819.
- Andersen LW, Liu X, Montissol S, Holmberg MJ, Sulmonte C, Balkema J, Cocchi MN, Gazmuri RJ, Berg K, Chase M. Cytochrome C in Patients with Septic Shock. Shock. 2016 May;45(5):512-517.
- Donnino MW, Andersen LW, Chase M, Berg K, Tidswell M, Giberson T, Wolfe R, Moskowitz A, Smithline H, Ngo L, Cocchi MN. Center for Resuscitation Science Research Group. Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study. Crit Care Med. 2016 Feb; 44(2):360-367.
- Donnino MW, Andersen LW, Berg K, Chase M, Sherwin R, Smithline H, Carney E, Ngo L, Patel PV, Liu X, Cutlip D, Zimetbaum P, Cocchi MN. collaborating authors from the Beth Israel Deaconess Medical Center’s Center for Resuscitation Science Research Group. Corticosteroid therapy in refractory shock following cardiac arrest: a randomized, double-blind, placebo-controlled, trial. Crit Care. 2016 Apr;20:82.
- Andersen LW, Holmberg MJ, Berg K, Chase M, Cocchi MN, Sulmonte C, Balkema J, MacDonald M, Montissol S, Senthilnathan V, Liu D, Khabbaz K, Lerner A, Novack V, Liu X, Donnino MW. Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-blind, placebo-controlled, phase II trial. Crit Care Med. 2016 Mar;20:92.
- Andersen LW, Kim WY, Chase M, Berg KM, Mortensen SJ, Moskowitz A, Novack V, Cocchi MN, Donnino MW; American Heart Association’s Get With the Guidelines(®) – Resuscitation Investigators. The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest. Resuscitation. 2016 Jan; 98: 112-117.
- Andersen LW, Liu X, Montissol S, Holmberg MJ, Sulmonte C, Balkema JL, Cocchi MN, Gazmuri RJ, Berg KM, Chase M, Donnino MW. Cytochrome C in Patients with Septic Shock. Shock. 2016 May; 45(5):512-517.
- Donnino MW, Anderson LW, Chase M, Berg KM, Tidswell M, Giberson T, Wolfe R, Moskowitz A, Smithline H, Ngo L, Cocchi MN; Center for Resuscitation Science Research Group. Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study. Crit Care Med. 2016 Feb; 44(2):360-367.
- Donnino MW, Andersen LW, Berg KM, Chase M, Sherwin R, Smithline H, Carney E, Ngo L, Patel PV, Liu X, Cutlip D, Zimetbaum P, Cocchi MN; Collaborating Authors from the Beth Israel Deaconess Medical Center’s Center for Resuscitation Science Research Group. Corticosteroid therapy in refractory shock following cardiac arrest: a randomized, double-blind, placebo-controlled, trial. Crit Care. 2016 Apr;20:82.
- Andersen LW, Holmberg MJ, Berg KM, Chase M, Cocchi MN, Sulmonte C, Balkema J, MacDonald M, Montissol S, Senthilnathan V, Liu D, Khabbaz K, Lerner A, Novack V, Liu X, Donnino MW. Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-blind, placebo-controlled, phase II trial. Crit Care. 2016 Mar;20:92.
- Andersen LW, Kurth T, Chase M, Berg KM, Cocchi MN, Callaway C, Donnino MW; American Heart Association’s Get With The Guidelines-Resuscitation Investigators. Early administration of epinephrine (adrenaline) in patients with cardiac arrest with initial shockable rhythm in hospital: propensity score matched analysis. BMJ. 2016 Apr; 353:i1577.
- Andersen LW, Berg KM, Chase M, Cocchi MN, Massaro J, Donnino MW; American Heart Association’s Get With The Guidelines(®)-Resuscitation Investigators. Acute respiratory compromise on inpatient wards in the United States: incidence, outcomes, and factors associated with in-hospital mortality. Resuscitation. 2016 Aug;105:123-129.
- Ghosh CC, Thamm K, Berghelli AV, Schrimpf C, Maski MR, Abid T, Milam K, Rajakumar A, Santel A, Kielstein J, Ahmed A, Thickett D, Wang K, Chase M, Donnino MW, Aird WC, Haller H, David S, Parikh SM. Drug repurposing screen identifies Foxo1-dependent Angiopoietin-2 regulation in sepsis. 2015 Jul;43(7):e230-240.
- Donnino MW, Mortensen SJ, Andersen LW, Chase M, Berg KM, Balkema J, Radhakrishnan J, Gazmuri RJ, Liu X, Cocchi MN. Ubiquinol (reduced Coenzyme Q10) in patients with severe sepsis or septic shock – a randomized, double-blind, placebo-controlled pilot trial. Crit Care. 2015 Jul; 19:275.
- Flaherty SK, Weber RL, Chase M, Dugas AF, Graver AM, Salciccioli JD, Cocchi MN, Donnino MW. Septic shock and adequacy of early empiric antibiotics in the emergency department. J Emerg Med. 2014 Nov;47(5):601-607.
- Chase M, Joyce NR, Carney E, Salciccioli JD, Vinton D, Donnino MW, Edlow JA. ED patients with vertigo: can we identify clinical factors associated with acute stroke? Am J Emerg Med. 2012 May;30(4):587-591.
- Chase M, Klasco RS, Joyce NR, Donnino MW, Wolfe RE, Shapiro NI. Predictors of bacterimia in emergency department patients with suspected infections. Am J Emerg Med. 2012 Nov;30(9):1691-1697.
- Salciccioli JD, Cristia C, Chase M, Giberson T, Graver A, Gautam S, Cocchi MN, Donnino MW. Performance of SAPS II and SAPS III scores in post-cardiac arrest. Minerva Anestesiol. 2012 Dec;78(12):1341-1347.
- Donnino MW, Carney E, Cocchi MN, Barbash I, Chase M, Joyce N, Chou PP, Ngo L. Thiamine deficiency in critically ill patients with sepsis. J Crit Care. 2010 Dec; 25(4):576-581.
- Donnino MW, Cocchi MN, Howell M, Clardy P, Talmor D, Cataldo L, Chase M, Al-Marshad A, Ngo, L, Shapiro NI. Statin therapy is associated with decreased mortality in patients admitted with infection. Acad Emerg Med. 2009 Mar;16(3):230-234.