About Anne Grossestreuer
Dr. Anne Grossestreuer is a Research Scientist in the Department of Emergency Medicine at Beth Israel Deaconess Medical Center, an Assistant Professor of Emergency Medicine at Harvard Medical School, and the Director of Epidemiology and Data Science at the Center for Resuscitation Science. She received her doctorate in Epidemiology from the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania. Dr. Grossestreuer’s research interests center on the definitive/supportive care that patients receive following successful resuscitation as well as outcomes after patients leave the hospital following critical illness. She is the Principal Investigator on an award from the Harvard Catalyst Medical Research Investigator Training that uses smartphones to assess the quality of life of patients after they leave the ICU and compares that to physician assessments. She is also the lead statistician for the ACTS trial and provides statistical support for a variety of other studies within Emergency Medicine and Critical Care as well as the BIDMC Data Abstraction Core. Dr. Grossestreuer is a member of the Editorial Board of Resuscitation and the American Heart Association’s Get with the Guidelines – Resuscitation Adult Research Taskforce. Formerly, she was the Principal Investigator on a grant from the American Heart Association, which supported her dissertation research on the association of post-arrest body temperature to neurologic and survival outcomes. Her research has won awards at the American Heart Association Resuscitation Science Symposium and the European Resuscitation Council Congress. She has additional research training in medical anthropology, in which she received an MSc from the University of Pennsylvania, and experience in health services research as a fellow at the Leonard Davis Institute of Healthcare Economics and health policy as a fellow at the Center for Emergency Care Policy Research.
Topics for Talks by Anne Grossestreuer
- Adaptive Clinical Trials
- Sensitivity and Specificity
- Introductory Biostatistics (short overview)
- Presentation of Data
- Ilg A, Moskowitz A, Konanki V, Patel PV, Chase M, Grossestreuer AV, Donnino MW. Performance of the CURB-65 Score in Predicting Critical Care Interventions in Patients Admitted with Community-Acquired Pneumonia. Ann Emerg Med. 2018 Aug; [Epub ahead of print].
- Holmberg MJ, Uber A, Stankovic N, Chen CO, Grossestreuer AV, Donnino MW, Andersen LW, Liu X. Ubiquinol (Reduced Coenzyme Q10) and Cellular Oxygen Consumption in Patients Undergoing Coronary Artery Bypass Grafting. J Intensive Care Med. 2018 Jan:[Epub ahead of print].
- Liu X, Montissol S, Uber A, Ganley S, Grossestreuer AV, Berg K, Heydrick S, Donnino MW. The Effects of Thiamine on Breast Cancer Cells. Molecules. 2018 Jun; 23(6).
- Uber A, Grossestreuer AV, Ross CE, Patel PV, Trehan A, Donnino MW, Berg KM. Preliminary observations in systemic oxygen consumption during targeted temperature management after cardiac arrest. Resuscitation. 2018 Jun; 127:89-94.
- Uber AJ, Perman SM, Cocchi MN, Patel PV, Ganley SE, Portmann JM, Donnino MW, Grossestreuer AV. Increased Heat Generation in Postcardiac Arrest Patients During Targeted Temperature Management Is Associated With Better Outcomes. Crit Care Med. 2018 Jul; 46(7):1133-1138.
- Andersen LW, Grossestreuer AV, Donnino MW. “Resuscitation time bias”-A unique challenge for observational cardiac arrest research. Resuscitation. 2018 Apr; 125:79-82.
- Moskowitz A, Grossestreuer AV, Berg KM, Patel PV, Ganley S, Casasola Medrano M, Cocchi MN, Donnino MW; Center for Resuscitation Science. The association between tidal volume and neurological outcome following in-hospital cardiac arrest. Resuscitation. 2018 Mar; 124:106-111.
- Holmberg MJ, Moskowitz A, Raymond TT, Berg RA, Nadkarni VM, Topjian AA, Grossestreuer AV, Donnino MW, Andersen LW; American Heart Association’s Get With The Guidelines-Resuscitation Investigators. Derivation and Internal Validation of a Mortality Prediction Tool for Initial Survivors of Pediatric In-Hospital Cardiac Arrest. Pediatr Cri Care Med. 2018 Mar; 19(3):186-195.
- Holmberg MJ, Moskowitz A, Patel PV, Grossestreuer AV, Uber A, Stankovic N, Andersen LW, Donnino MW. Thiamine in septic shock patients with alcohol use disorders: An observational pilot study. J Crit Care. 2018 Feb; 43:61-64.
- Moskowitz A, Andersen LW, Huang DT, Berg KM, Grossestreuer AV, Marik PE, Sherwin RL, Hou PC, Becker LB, Cocchi MN, Doshi P, Gong J, Sen A, Donnino MW. Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation. Crit Care. 2018 Oct 29;22(1):283.
- Moskowitz A, Ross CE, Andersen LW, Grossestreuer AV, Berg KM, Donnino MW, American Heart Association’s Get With The Guidelines — Resuscitation Investigators. Crit Care Med. 2018 Nov 7. [Epub ahead of print].
- Donnino MW, Liu X, Andersen LW, Rittenberger JC, Abella BS, Gaieski D, Ornato J, Gazmuri RJ, Grossestreuer AV, Cocchi MN, Abbate A, Uber A, Clore J, Peberdy MA, Callaway CW. Characterization of Mitochondrial Injury after Cardiac Arrest (COMICA). Resuscitation. 2017 Apr;113:56-62.
- Moskowitz A, Andersen LW, Karlsson M, Grossestreuer AV, Chase M, Cocchi MN, Berg K, Donnino MW. Predicting In-Hospital Mortality for Initial Survivors of Acute Respiratory Compromise (ARC) events: Development and Validation of the ARC Score. Resuscitation. 2017 Jun;115:5-10.
- Grossestreuer AV, Gaieski D, Donnino MW, Wiebe DJ, Abella BS. Magnitude of Temperature Elevation is Associated with neurologic and Survival Outcomes in Resuscitated Cardiac arrest Patients with Postrewarming Pyrexia. J Crit Care. 2017 Apr;38:78-83.
- Grossestreuer AV, Gaieski DF, Donnino MW, Nelson JIM, Mutter EL, Carr BG, Abella BS, Wiebe DJ. Cardiac arrest risk standardization using administrative data compared to registry data. PLoS One. 2017 Aug;12(8):e0182864.
- Moskowitz A, Patel PV, Grossestreuer AV, Chase M, Shapiro NI, Berg K, Cocchi MN, Holmberg MJ, Donnino MW; Center for Resuscitation Science. Quick Sequential Organ Failure Assessment and Systemic Inflammatory Response Syndrome Criteria as Predictors of Critical Care Intervention Among Patients With Suspected Infection. Crit Care Med. 2017 Nov;45(11):1813-1819.
- Berg KM, Grossestreuer AV, Uber A, Patel PV, Donnino MW. Intubation is not a marker for coma after in-hospital cardiac arrest: A retrospective study. Resuscitation. 2017 Oct; 119:18-20.
- Peberdy MA, Andersen LW, Abbate A, Thacker LR, Gaieski D, Abella BS, Grossestreuer AV, Rittenberger JC, Clore J, Ornato J, Cocchi MN, Callaway CW, Donnino MW. National Post Arrest Research Consortium (NPARC) Investigators. Inflammatory markers following resuscitation from out-of-hospital cardiac arrest-A prospective multicenter observational study. Resuscitation. 2016 Jun; 103:117-124.
- Andersen LW, Raymond TT, Berg RA, Nadkarni VM, Grossestreuer AV, Kurth T, Donnino MW; American Heart Association’s Get With The Guidelines–Resuscitation Investigators. Association Between Tracheal Intubation During Pediatric In-Hospital Cardiac Arrest and Survival. JAMA. 2016 Nov; 316(17):1786-1797.
- Peberdy MA, Andersen LW, Abbate A, Thacker LR, Gaieski D, Abella BS, Grossestreuer AV, Rittenberger JC, Clore J, Ornato J, Cocchi MN, Callaway C, Donnino M; National Post Arrest Research Consortium (NPARC) Investigators. Inflammatory markers following resuscitation from out-of-hospital cardiac arrest-a prospective multicenter observational study. Resuscitation. 2016 Jun; 103:117-124.
- Donnino MW, Andersen LW, Giberson T, Gaiski DF, Abella BS, Peberdy MA, Rittenberger JC, Callaway CW, Ornato J, Clore J, Grossestreuer A, Salccioli J, Cocchi MN; National Post-Arrest Research Consortium. Initial lactate and lactate change in post-cardiac arrest: a multicenter validation study. Crit Care Med. 2014 Aug;42(8):1804-1811.