Dr. Lee is a Clinical Instructor at Harvard Medical School and an attending emergency physician at Beth Israel Deaconess Medical Center. As a physician-engineer, he works at the intersection of clinical medicine, engineering, and technology. He studied electrical engineering at Cornell University and subsequently worked as an integrated circuit designer at Advanced Micro Devices before earning his MS and PhD in electrical engineering from MIT, where his research focused on the development of novel medical devices. He received his MD from the University of Chicago and completed his residency in emergency medicine at Beth Israel Deaconess Medical Center.
Dr. Lee subsequently completed a T32 Research Fellowship in Resuscitation Science at the Center for Resuscitation Science, where he now serves as Director of Technology and AI. His research focuses on developing and applying artificial intelligence, advanced physiologic monitoring, and novel technologies to improve the recognition, monitoring, and care of critically ill patients.
Video-based patient monitoring
Improving quality of care using AI
Microcirculation in critical illness
Mitochondrial dysfunction in critical illness
Latest Publications:
Vine J, Lee JH, Simpson MD, Grossestreuer AV, Sorour K, Zubair MM, Moskowitz A, Berg KM, Liu X, Donnino MW. Baseline Measurements of Cellular Respiration Affect the Response to Thiamine Treatment in Post-Arrest Patients. Resuscitation. 2026 Feb 25;0(0). doi:10.1016/j.resuscitation.2026.111029
Lee JH, Vine J, Balaji L, Peradze N, Antony N, Wang Y, Morton A, Moskowitz A, Donnino MW, Liu X. Mitochondrial Respiration in Peripheral Blood Mononuclear Cells of Healthy Adult Population. PLOS ONE. 2026.
Ross CE, Lee JH, Loaec M, Valdés SO, Donnino MW, Berg RA. Cardiac Arrest Pharmacopeia: A Personalized Approach to Drug Administration During Cardiopulmonary Resuscitation. Critical Care Clinics. 2025 Sep 13. doi:10.1016/j.ccc.2025.08.005
Lee JH, Vine J, Meier M, Berkovitz A, Balaji L, Grossestreuer AV, Moskowitz A, Berg KM, Donnino MW. The Impact of Extended-Hours Patient Recruitment on Critical Care Clinical Trial Enrollment. Critical Care Explorations. 2025 Apr;7(4):e1239. doi:10.1097/CCE.0000000000001239
Vine J, Lee JH, Moskowitz A, Donnino MW. Thiamine administration in septic shock: towards finding the target population. Crit Care. 2024 Dec 18;28(1):422. Doi:10.1186/s13054-024-05209-2
Kravitz MS, Lee JH, Shapiro NI. Cardiac arrest and microcirculatory dysfunction: a narrative review. Curr Opin Crit Care. 2024 Dec 1;30(6):611–7. doi:10.1097/MCC.0000000000001219 PubMed PMID: 39377652; PubMed Central PMCID: PMC11540727.
Bhargava A, López-Espina C, Schmalz L, Khan S, Watson GL, Urdiales D, Updike L, Kurtzman N, Dagan A, Doodlesack A, Stenson BA, Sarma D, Reseland E, Lee JH, Kravitz MS, Antkowiak PS, Shvilkina T, Espinosa A, Halalau A, Demarco C, Davila F, Davila H, Sims M, Maddens N, Berghea R, Smith S, Palagiri AV, Ezekiel C, Sadaka F, Iyer K, Crisp M, Azad S, Oke V, Friederich A, Syed A, Gosai F, Chawla L, Evans N, Thomas K, Malkani R, Patel R, Mayer S, Ali F, Raghavakurup L, Tafa M, Singh S, Raouf S, Zhao SD, Zhu R, Bashir R, Reddy B, Shapiro NI. FDA-Authorized AI/ML Tool for Sepsis Prediction: Development and Validation. NEJM AI. 2024 Nov 27;1(12):AIoa2400867. doi:10.1056/AIoa2400867
Vine J, Lee JH, Balaji L, Grossestreuer AV, Morton A, Peradze N, Antony N, Berlin N, Kravitz MS, Leland SB, Berg K, Moskowitz A, Donnino MW, Liu X. Cellular oxygen consumption in patients with diabetic ketoacidosis. ICMx. 2024 Nov 4;12(1):97. doi:10.1186/s40635-024-00673-0
Vine J, Lee JH, Kravitz MS, Grossestreuer AV, Balaji L, Leland SB, Berlin N, Moskowitz A, Donnino MW. Thiamine administration in septic shock: a post hoc analysis of two randomized trials. Critical Care. 2024 Feb 6;28(1):41. doi:10.1186/s13054-024-04818-1
Lee JH, Nathanson LA, Burke RC, Anthony BW, Shapiro NI, Dagan AS. Assessment of respiratory rate monitoring in the emergency department. Journal of the American College of Emergency Physicians Open. 2024;5(3):e13154. doi:10.1002/emp2.13154
Lee JH, Traverso G, Ibarra-Zarate D, Boning DS, Anthony BW. Ex Vivo and In Vivo Imaging Study of Ultrasound Capsule Endoscopy. Journal of Medical Devices. 2020 Mar 18;14(021005):021005. doi:10.1115/1.4046352
Li H, Mendel KR, Lee JH, Lan L, Giger ML. Deep learning in breast cancer risk assessment: evaluation of fine-tuned convolutional neural networks on a clinical dataset of FFDMs. In: Medical Imaging 2018: Computer-Aided Diagnosis. Houston, TX: SPIE; 2018. p. 180–5. doi:10.1117/12.2294536
Lee JH, Grant BR, Chung JH, Reiser I, Giger M. Assessment of diagnostic image quality of computed tomography (CT) images of the lung using deep learning. In: Medical Imaging 2018: Physics of Medical Imaging. Houston, TX: SPIE; 2018. p. 399–405. doi:10.1117/12.2292070
Lee JH, Boning DS, Anthony BW. Measuring the Absolute Concentration of Microparticles in Suspension Using High-Frequency B-Mode Ultrasound Imaging. Ultrasound Med Biol. 2018;44(5):5. doi:10.1016/j.ultrasmedbio.2018.01.008 PubMed PMID: 29482889.