Establishment of a reference interval for thiamine concentrations in healthy dogs and evaluation of the prevalence of absolute thiamine deficiency in critically ill dogs with and without sepsis using high-performance liquid chromatography.
In an exciting collaborative pilot study led by our former T32 Fellow, Noa Berlin, thiamine levels were lower in dogs with sepsis compared to healthy controls and to non-septic critically-ill dogs, paving the way for exciting translational research in metabolic resuscitation.